NEUROPSYCHOLOGY & BEHAVIORAL NEUROSCIENCE

C J Long


CONTENTS

Series Overview
Predoctoral Training
The UM Program
References

PHYSIOLOGICAL

Introduction
Neuron
Supporting Cells
Resting Potential
Action Potential
Synaptic Connections
Techniques
Organizational Plan
Pharmacology
Neural Coding
Vision
Audition
Somatosensory
Thalamus
Cortex
Brain Mechanisms & Movement
Reflexes & Reflex Integration
Cerebellum
Activation
Sleep
Attention
Emotion
Theories of Emotion
Homeostasis
Memory
Learning
Disorders of CNS

NEUROPSYCHOLOGY

Intro. to Neuropsyc.
History of Neuropsyc.
Brain-Behavior Summary
Brain-Behavior Detailed
Cerebrum Review

NEUROPATHOLOGY

Neuropathology
Neurological Exam
Neoplastic Processes
Vascular Disorders
Traumatic Brain Injury
Infectious Diseases
Dementia

ISSUES

Overview of Issues
Localization?
1CHP&WOL doc
2CHP&WOL DOC
Connectionistic
Hierarchical Systems
Qualitative vs Quantitative
Battery vs Individualized
Frontal Lobe Function
Temporal Lobe Function
Parietal Lobe Function
Occipital Lobe Function

ASSESSMENT STRATEGIES

Assessment Approach
Eval. Sequence
Hisory: Outline
History for TBI

Mental Status
Test Reviews
General Screening Devices
Test Batteries
Localization
Dysfunction
Age Norms for HRB
Report Outline
Sample Report
Misconceptions

THE DATA BASE

Information Source
Demographics
Test Behavior
History
Situational Factors
Neuropsychological Data
Etiology

DECISION STRATEGIES

DEV-PLAN.DOC
DEC-NAN.DOC
DEC-III.DOC
DECIS-91.DOC
CRITERIA.DOC
Computational Models
Hartlage.doc

ASSESSMENT ISSUES

DISABILI.DOC
DVR.DOC
DVR-S.DOC
DVR.DOC

TREATMENT

WEB SITES

REFERENCES

Bulletin Board

NP HOME

CJ's HOME

Examination of Patient


Overview of Topics

General Aspects of Examination
Neurological Examination
Neurovascular Examination
Differential Diagnosis
International Classification of Seizures


General

  1. Examine head for evidence of injury.
  2. Optic discs
  3. Odor of breath
  4. Temp, BP, resp, pulse
  5. W/major vessel - temp. may be elevated and heart rate increased.


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Neurologic Examination

  1. Important to determine if hemplegia is present.
    1. look at facial muscles for signs of flacidity during respiration.
    2. raise limbs & let fall - paralyzed limbs fall heavily, others will sink gradually to bed.
    3. vigorous stimulation of sole of foot will cause withdrawal in unparalyzed limbs.

  2. Cortical lesion - pupils may be unequal in size. (larger one on the side opposite the lesion).

  3. Conjugate deviation of the head and eyes together.
    1. deviation toward the side of lesion in cortical abnormalities.
    2. away from it in brain stem abnormalities.

  4. Stiffness of the neck - related to the presence of blood in the spinal fluid.


Neurovascular Examination

  1. Neck flexion - as above.
  2. Palpation -
    1. superficial temporal artery
    2. internal carotid
    3. radial artery
  3. Auscultation
  4. Opthalmodynamometry


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Differential Diagnosis

  1. Focal or general neurologic symptoms appear suddenly in a patient with hypertension, arteriosclerosis, or other evidence of vascular disease.

  2. Diagnosis is a two-fold process
    1. Determine CVA Vs infections, degeneration, or neoplasm.
    2. Determine form of CV disorder -
      • infarction ,
      • hemorrhage
      • embolus

  3. Extradural hemorrhage
    1. symptoms appear immediately following a blow to the head.

  4. Subdural hematoma
    1. prompt diagnosis important as operation may be necessary to save patient’s life.
    2. may occur with hypertension.
    3. symptoms may not appear for several weeks.

  5. Neoplasm or Abscess
    1. usually slow and progressive development of symptoms.
    2. choked disc
    3. normal blood pressure
    4. clear cerebrospinal fluid
    5. abscess - same except cerebrospinal fluid shows mild to moderate pleocytosis.

  6. Cerebral Embolism
    1. sudden onset of neurologic symptoms
    2. acute or chronic endocarditis
      • atrial fibrillation
      • recent myocardial infarction
      • septicemia
      • septic focus

  7. Cerebral Hemorrhage
    1. Difficult to distinguish from infarction since both occur in same age group with arteriosclerosis and hypertension.
    2. Cerebral hemorrhage
      • convulsions (twice as frequent as patients with Infarction)
      • severe headache, nausea, vomiting, at onset.
      • Cheyne - Stokes or labored respiration
      • Conjugate deviation of the eyes
      • Stiffness of the neck
      • Quadriplegia
      • Bilateral Babinski
      • Bloody cerebrospinal fluid.


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International Classification of Epileptic Seizures

(Gastaut, 1970)

Old terms such as "grand mal". "petit mal", "jacksonian", and "temporal lobe" have been discarded in favor of more descriptive terms.

I. Partial Seizures
A. Partial seizures with elementary symptomatology (without impairment of consciousness)

  1. Motor symptoms (jacksonian included)
  2. Special sensory or somatosensory symptoms (visual, auditory, olfactory, vertigenous, abdominal)
  3. Autonomic symptoms (nausea, vomiting, flushing, HR changes)
  4. Compound forms

B. Partial seizures with complex symptomatology (generally impaired consciousness - includes temporal lobe or psychomotor)

  1. With impairment of consciousness only
  2. Cognitive symptoms
  3. Affective symptoms
  4. Psychosensory symptoms
  5. Psychomotor (automatism’s)
  6. Compound

C. Partial seizures secondarily generalized

II. Generalized Seizures (bilaterally symmetrical and without focal onset/centrencephalic - originate in diencephalon)

  1. Absences (petit mal)
  2. Bilateral massive epileptic myoclonous
  3. Infantile spasms
  4. Clonic seizures
  5. Tonic seizures
  6. Tonic - clonic seizures (grand mal)
  7. Atonic seizures
  8. Kinetic seizures.

III. Unilateral Seizures (or predominantly)

IV. Unclassified Epileptic Seizures (due to incomplete data)


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